Intraparenchymal Hemorrhage: A Fatal Presentation of Undiagnosed Acute Myelogenous Leukemia

We present the case of a 73-year-old patient who was admitted to the neurocritical care unit with spontaneous intracerebral hemorrhage (ICH). Upon further investigation, she was found to have hyperleukocytosis and thrombocytopenia due to acute myelogenous leukemia (AML), likely resulting in coagulop...

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Detalles Bibliográficos
Autores principales: Hamadi, Rachelle, Assaad, Marc, Zurndorfer, Juda, El Gharib, Khalil, Kwok, Raymond, Dhar, Meekoo, Schwab, Alfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250100/
https://www.ncbi.nlm.nih.gov/pubmed/35795513
http://dx.doi.org/10.7759/cureus.25592
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author Hamadi, Rachelle
Assaad, Marc
Zurndorfer, Juda
El Gharib, Khalil
Kwok, Raymond
Dhar, Meekoo
Schwab, Alfred
author_facet Hamadi, Rachelle
Assaad, Marc
Zurndorfer, Juda
El Gharib, Khalil
Kwok, Raymond
Dhar, Meekoo
Schwab, Alfred
author_sort Hamadi, Rachelle
collection PubMed
description We present the case of a 73-year-old patient who was admitted to the neurocritical care unit with spontaneous intracerebral hemorrhage (ICH). Upon further investigation, she was found to have hyperleukocytosis and thrombocytopenia due to acute myelogenous leukemia (AML), likely resulting in coagulopathy, vessel friability, and consequential intraparenchymal bleed. Prior reports of AML presenting with ICH are scant in the literature. As such, a heightened awareness of such a phenomenon is recommended for rapid detection and appropriate tailored management. This hopefully would, in turn, optimize outcomes.
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spelling pubmed-92501002022-07-05 Intraparenchymal Hemorrhage: A Fatal Presentation of Undiagnosed Acute Myelogenous Leukemia Hamadi, Rachelle Assaad, Marc Zurndorfer, Juda El Gharib, Khalil Kwok, Raymond Dhar, Meekoo Schwab, Alfred Cureus Neurology We present the case of a 73-year-old patient who was admitted to the neurocritical care unit with spontaneous intracerebral hemorrhage (ICH). Upon further investigation, she was found to have hyperleukocytosis and thrombocytopenia due to acute myelogenous leukemia (AML), likely resulting in coagulopathy, vessel friability, and consequential intraparenchymal bleed. Prior reports of AML presenting with ICH are scant in the literature. As such, a heightened awareness of such a phenomenon is recommended for rapid detection and appropriate tailored management. This hopefully would, in turn, optimize outcomes. Cureus 2022-06-02 /pmc/articles/PMC9250100/ /pubmed/35795513 http://dx.doi.org/10.7759/cureus.25592 Text en Copyright © 2022, Hamadi et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurology
Hamadi, Rachelle
Assaad, Marc
Zurndorfer, Juda
El Gharib, Khalil
Kwok, Raymond
Dhar, Meekoo
Schwab, Alfred
Intraparenchymal Hemorrhage: A Fatal Presentation of Undiagnosed Acute Myelogenous Leukemia
title Intraparenchymal Hemorrhage: A Fatal Presentation of Undiagnosed Acute Myelogenous Leukemia
title_full Intraparenchymal Hemorrhage: A Fatal Presentation of Undiagnosed Acute Myelogenous Leukemia
title_fullStr Intraparenchymal Hemorrhage: A Fatal Presentation of Undiagnosed Acute Myelogenous Leukemia
title_full_unstemmed Intraparenchymal Hemorrhage: A Fatal Presentation of Undiagnosed Acute Myelogenous Leukemia
title_short Intraparenchymal Hemorrhage: A Fatal Presentation of Undiagnosed Acute Myelogenous Leukemia
title_sort intraparenchymal hemorrhage: a fatal presentation of undiagnosed acute myelogenous leukemia
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250100/
https://www.ncbi.nlm.nih.gov/pubmed/35795513
http://dx.doi.org/10.7759/cureus.25592
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