The impact of HIV infection on the frequencies, function, spatial localization and heterogeneity of T follicular regulatory cells (TFRs) within human lymph nodes

BACKGROUND: HIV eradication efforts have been unsuccessful partly due to virus persistence in immune sanctuary sites such as germinal centres within lymph node (LN) tissues. Recent evidence suggests that LNs harbour a novel subset of regulatory T cells, termed follicular regulatory T cells (TFRs), b...

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Detalles Bibliográficos
Autores principales: Mahlobo, Bongiwe, Laher, Faatima, Smidt, Werner, Ogunshola, Funsho, Khaba, Trevor, Nkosi, Thandeka, Mbatha, Anele, Ngubane, Thandekile, Dong, Krista, Jajbhay, Ismail, Pansegrouw, Johan, Ndhlovu, Zaza M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250173/
https://www.ncbi.nlm.nih.gov/pubmed/35778692
http://dx.doi.org/10.1186/s12865-022-00508-1

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