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Population pharmacokinetic modeling of CSF to blood clearance: prospective tracer study of 161 patients under work-up for CSF disorders

BACKGROUND: Quantitative measurements of cerebrospinal fluid to blood clearance has previously not been established for neurological diseases. Possibly, variability in cerebrospinal fluid clearance may affect the underlying disease process and may possibly be a source of under- or over-dosage of int...

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Detalles Bibliográficos
Autores principales:	Hovd, Markus Herberg, Mariussen, Espen, Uggerud, Hilde, Lashkarivand, Aslan, Christensen, Hege, Ringstad, Geir, Eide, Per Kristian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250213/ https://www.ncbi.nlm.nih.gov/pubmed/35778719 http://dx.doi.org/10.1186/s12987-022-00352-w

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