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A mechanistic motor-clutch model that explains cell shape dynamics to cyclic stretch

Many cells in the body experience cyclic mechanical loading, which can impact cellular processes and morphology. In vitro studies often report that cells reorient in response to cyclic stretch of their substrate. To explore cellular mechanisms involved in this reorientation, a computational model wa...

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Detalles Bibliográficos
Autores principales: Scandling, Benjamin W., Gou, Jia, Thomas, Jessica, Xuan, Jacqueline, Xue, Chuan, Gooch, Keith J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250388/
https://www.ncbi.nlm.nih.gov/pubmed/35020463
http://dx.doi.org/10.1091/mbc.E20-01-0087

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