Informing NMR experiments with molecular dynamics simulations to characterize the dominant activated state of the KcsA ion channel

As the first potassium channel with an x-ray structure determined, and given its homology to eukaryotic channels, the pH-gated prokaryotic channel KcsA has been extensively studied. Nevertheless, questions related, in particular, to the allosteric coupling between its gates remain open. The many cur...

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Detalles Bibliográficos
Autores principales: Pérez-Conesa, Sergio, Keeler, Eric G., Zhang, Dongyu, Delemotte, Lucie, McDermott, Ann E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2021
Materias:
ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250420/
https://www.ncbi.nlm.nih.gov/pubmed/33940802
http://dx.doi.org/10.1063/5.0040649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250420/
https://www.ncbi.nlm.nih.gov/pubmed/33940802
http://dx.doi.org/10.1063/5.0040649

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