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Informing NMR experiments with molecular dynamics simulations to characterize the dominant activated state of the KcsA ion channel
As the first potassium channel with an x-ray structure determined, and given its homology to eukaryotic channels, the pH-gated prokaryotic channel KcsA has been extensively studied. Nevertheless, questions related, in particular, to the allosteric coupling between its gates remain open. The many cur...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
AIP Publishing LLC
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250420/ https://www.ncbi.nlm.nih.gov/pubmed/33940802 http://dx.doi.org/10.1063/5.0040649 |