Low-dose sodium-glucose cotransporter 2 inhibitor ameliorates ischemic brain injury in mice through pericyte protection without glucose-lowering effects

Antidiabetic sodium-glucose cotransporter 2 (SGLT2) inhibitors have attracted attention for their cardiorenal-protective properties beyond their glucose-lowering effect. However, their benefits in ischemic stroke remain controversial. Here we show the effects of luseogliflozin, a selective SGLT2 inh...

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Detalles Bibliográficos
Autores principales: Takashima, Masamitsu, Nakamura, Kuniyuki, Kiyohara, Takuya, Wakisaka, Yoshinobu, Hidaka, Masaoki, Takaki, Hayato, Yamanaka, Kei, Shibahara, Tomoya, Wakisaka, Masanori, Ago, Tetsuro, Kitazono, Takanari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250510/
https://www.ncbi.nlm.nih.gov/pubmed/35780235
http://dx.doi.org/10.1038/s42003-022-03605-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250510/
https://www.ncbi.nlm.nih.gov/pubmed/35780235
http://dx.doi.org/10.1038/s42003-022-03605-4

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