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Protein and functional isoform levels and genetic variants of the BAFF and APRIL pathway components in systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is the prototype of an autoimmune disease. Belimumab, a monoclonal antibody targets BAFF, is the only biologic approved for SLE and active lupus nephritis. BAFF is a cytokine with a key-regulatory role in the B cell homeostasis, which acts by binding to three recep...

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Detalles Bibliográficos
Autores principales:	Ortiz-Aljaro, Pilar, Montes-Cano, Marco Antonio, García-Lozano, José-Raúl, Aquino, Virginia, Carmona, Rosario, Perez-Florido, Javier, García-Hernández, Francisco José, Dopazo, Joaquín, González-Escribano, María Francisca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250527/ https://www.ncbi.nlm.nih.gov/pubmed/35780200 http://dx.doi.org/10.1038/s41598-022-15549-0

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