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Ultrasmall Nanoparticle Delivery of Doxorubicin Improves Therapeutic Index for High-Grade Glioma

PURPOSE: Despite dramatic growth in the number of small-molecule drugs developed to treat solid tumors, durable therapeutic options to control primary central nervous system malignancies are relatively scarce. Chemotherapeutic agents that appear biologically potent in model systems have often been f...

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Detalles Bibliográficos
Autores principales: Aragon-Sanabria, Virginia, Aditya, Anusha, Zhang, Li, Chen, Feng, Yoo, Barney, Cao, Tianye, Madajewski, Brian, Lee, Rachel, Turker, Melik Z., Ma, Kai, Monette, Sebastien, Chen, Peiming, Wu, Jing, Ruan, Shutian, Overholtzer, Michael, Zanzonico, Pat, Rudin, Charles M., Brennan, Cameron, Wiesner, Ulrich, Bradbury, Michelle S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250642/
https://www.ncbi.nlm.nih.gov/pubmed/35499557
http://dx.doi.org/10.1158/1078-0432.CCR-21-4053