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Preparation of Zein-Based Nanoparticles: Nanoprecipitation versus Microfluidic-Assisted Manufacture, Effects of PEGylation on Nanoparticle Characteristics and Cellular Uptake by Melanoma Cells
BACKGROUND: The manufacture of nanoparticles using manual methods is hampered by its challenging scale-up and poor reproducibility. To overcome this issue, the production of zein nanoparticles entrapping a lipophilic drug model, coumarin-6, by using a microfluidic system was assessed in this study....
Autores principales: | Meewan, Jitkasem, Somani, Sukrut, Almowalad, Jamal, Laskar, Partha, Mullin, Margaret, MacKenzie, Graeme, Khadke, Swapnil, Perrie, Yvonne, Dufès, Christine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250780/ https://www.ncbi.nlm.nih.gov/pubmed/35791309 http://dx.doi.org/10.2147/IJN.S366138 |
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