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Preparation of Zein-Based Nanoparticles: Nanoprecipitation versus Microfluidic-Assisted Manufacture, Effects of PEGylation on Nanoparticle Characteristics and Cellular Uptake by Melanoma Cells

BACKGROUND: The manufacture of nanoparticles using manual methods is hampered by its challenging scale-up and poor reproducibility. To overcome this issue, the production of zein nanoparticles entrapping a lipophilic drug model, coumarin-6, by using a microfluidic system was assessed in this study....

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Detalles Bibliográficos
Autores principales: Meewan, Jitkasem, Somani, Sukrut, Almowalad, Jamal, Laskar, Partha, Mullin, Margaret, MacKenzie, Graeme, Khadke, Swapnil, Perrie, Yvonne, Dufès, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250780/
https://www.ncbi.nlm.nih.gov/pubmed/35791309
http://dx.doi.org/10.2147/IJN.S366138

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