TP53 variants in p53 signatures and the clonality of STICs in RRSO samples

OBJECTIVE: Precursor lesions may be identified in fallopian tube tissue after risk-reducing salpingo-oophorectomy (RRSO) in patients with pathogenic variants of BRCA1/2. Serous tubal intraepithelial carcinoma (STIC) is considered a precursor of high-grade serous carcinoma, whereas the significance o...

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Detalles Bibliográficos
Autores principales: Akahane, Tomoko, Masuda, Kenta, Hirasawa, Akira, Kobayashi, Yusuke, Ueki, Arisa, Kawaida, Miho, Misu, Kumiko, Nakamura, Kohei, Nagai, Shimpei, Chiyoda, Tatsuyuki, Yamagami, Wataru, Hayashi, Shigenori, Kataoka, Fumio, Banno, Kouji, Sugano, Kokichi, Okita, Hajime, Kosaki, Kenjiro, Nishihara, Hiroshi, Aoki, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology; Japan Society of Gynecologic Oncology 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250861/
https://www.ncbi.nlm.nih.gov/pubmed/35557033
http://dx.doi.org/10.3802/jgo.2022.33.e50

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