Amelioration of SARS-CoV-2 infection by ANO6 phospholipid scramblase inhibition

As an enveloped virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) delivers its viral genome into host cells via fusion of the viral and cell membranes. Here, we show that ANO6/TMEM16F-mediated cell surface exposure of phosphatidylserine is critical for SARS-CoV-2 entry and that ANO...

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Detalles Bibliográficos
Autores principales: Sim, Ju-Ri, Shin, Dong Hoon, Park, Pil-Gu, Park, So-Hyeon, Bae, Joon-Yong, Lee, Youngchae, Kang, Dha-Yei, Kim, Ye Jin, Aum, Sowon, Noh, Shin Hye, Hwang, Su Jin, Cha, Hye-Ran, Kim, Cheong Bi, Ko, Si Hwan, Park, Sunghoon, Jeon, Dongkyu, Cho, Sungwoo, Lee, Gee Eun, Kim, Jeonghun, Moon, Young-hye, Kim, Jae-Ouk, Nam, Jae-Sung, Kim, Chang-Hoon, Moon, Sungmin, Chung, Youn Wook, Park, Man-Seong, Ryu, Ji-Hwan, Namkung, Wan, Lee, Jae Myun, Lee, Min Goo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250890/
https://www.ncbi.nlm.nih.gov/pubmed/35839776
http://dx.doi.org/10.1016/j.celrep.2022.111117

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