An autopsy case report of fulminant myocarditis: Following mRNA COVID-19 vaccination

There have been few case reports on fatal outcomes in patients with acute myocarditis after mRNA coronavirus disease 2019 (COVID-19) vaccination. In most cases of myocarditis after mRNA COVID-19 vaccination, the myocarditis is mild, and the prognosis is good. Here we report an autopsy case of fulmin...

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Detalles Bibliográficos
Autores principales: Hoshino, Naoki, Yanase, Masanobu, Ichiyasu, Taisuke, Kuwahara, Kazuhiko, Kawai, Hideki, Muramatsu, Takashi, Ishii, Hideki, Tsukamoto, Tetsuya, Morimoto, Shin-ichiro, Izawa, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese College of Cardiology 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250935/
https://www.ncbi.nlm.nih.gov/pubmed/35812802
http://dx.doi.org/10.1016/j.jccase.2022.06.006
Descripción
Sumario:There have been few case reports on fatal outcomes in patients with acute myocarditis after mRNA coronavirus disease 2019 (COVID-19) vaccination. In most cases of myocarditis after mRNA COVID-19 vaccination, the myocarditis is mild, and the prognosis is good. Here we report an autopsy case of fulminant myocarditis following mRNA COVID-19 vaccination. LEARNING OBJECTIVE: The global distribution of the mRNA coronavirus disease 2019 vaccine requires consideration of appropriate treatment for postvaccination myocarditis. Eosinophil-mediated immunological injury to cardiomyocytes can be involved in the cause of fulminant inflammation from the pathological findings of postvaccination myocarditis.

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