Pipersentan: A De Novo Synthetic Endothelin Receptor Antagonist that Inhibits Monocrotaline- and Hypoxia-Induced Pulmonary Hypertension

Background: Although major advances have been made in the pathogenesis and management of pulmonary arterial hypertension (PAH), the endothelin system is still considered to play a vital role in the pathology of PAH due to its vasoconstrictive action. Endothelin receptor antagonists (ERAs), either as...

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Detalles Bibliográficos
Autores principales: Zhang, Zeyu, Liu, Chunlei, Bai, Yongyi, Li, Xin, Gao, Xiaojian, Li, Chen, Guo, Ge, Chen, Si, Sun, Mingzhuang, Liu, Kang, Li, Yang, He, Kunlun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251115/
https://www.ncbi.nlm.nih.gov/pubmed/35795553
http://dx.doi.org/10.3389/fphar.2022.920222

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