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Smad7 Is Highly Expressed in Human Degenerative Discs and Participates in IL-1β-Induced Apoptosis of Rat AF Cells via the Mitochondria Pathway
BACKGROUND: Abnormal Smad7 expression can lead to apoptosis in different cell types. Previously, we found high expression of Smad7 in rat degenerative discs. However, the exact role of Smad7 in the apoptosis of disc cells and the possible underlying mechanism remain unclear. METHODS: Degenerative an...
Autores principales: | Li, Bo, Lu, Ze-Yu, Jiang, Sheng-Dan, Jiang, Lei-Sheng, Zheng, Xin-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251149/ https://www.ncbi.nlm.nih.gov/pubmed/35795857 http://dx.doi.org/10.1155/2022/2912276 |
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