Assessment of the stability of citrate-buffered piperacillin/tazobactam for continuous infusion when stored in two commercially available elastomeric devices for outpatient parenteral antimicrobial chemotherapy: a study compliant with the NHS Yellow Cover Document requirements

OBJECTIVES: To investigate the effect of pH control through the use of a citrate-buffered saline diluent pH 7 on the degradation rate of piperacillin/tazobactam solutions for infusion and to determine if an extended shelf-life of up to 13 days fridge 2°C–8°C plus 24 hours ‘in-use’ at 32°C in two ela...

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Detalles Bibliográficos
Autores principales: Jamieson, Conor, Ozolina, Laima, Seaton, R Andrew, Gilchrist, Mark, Hills, Tim, Drummond, F, Wilkinson, Alan Shaun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251159/
https://www.ncbi.nlm.nih.gov/pubmed/32978220
http://dx.doi.org/10.1136/ejhpharm-2020-002340

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