Cargando…

Lentiviral interferon: A novel method for gene therapy in bladder cancer

Interferon alpha (IFNα) gene therapy is emerging as a new treatment option for patients with non-muscle invasive bladder cancer (NMIBC). Adenoviral vectors expressing IFNα have shown clinical efficacy treating bacillus Calmette-Guerin (BCG)-unresponsive bladder cancer (BLCA). However, transient tran...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mokkapati, Sharada, Narayan, Vikram M., Manyam, Ganiraju C., Lim, Amy H., Duplisea, Jonathan J., Kokorovic, Andrea, Miest, Tanner S., Mitra, Anirban P., Plote, Devin, Anand, Selvalakshmi Selvaraj, Metcalfe, Michael J., Dunner, Kenneth, Johnson, Burles A., Czerniak, Bogdan A., Nieminen, Tiina, Heikura, Tommi, Yla-Herttuala, Seppo, Parker, Nigel R., Schluns, Kimberley S., McConkey, David J., Dinney, Colin P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251210/ https://www.ncbi.nlm.nih.gov/pubmed/35847448 http://dx.doi.org/10.1016/j.omto.2022.06.005

Ejemplares similares

Inhibition of urothelial carcinoma through targeted type I interferon-mediated immune activation
por: Plote, Devin, et al.
Publicado: (2019)

Benchmarking of Scale-X Bioreactor System in Lentiviral and Adenoviral Vector Production
por: Leinonen, Hanna M., et al.
Publicado: (2020)

Snake venom VEGF Vammin induces a highly efficient angiogenic response in skeletal muscle via VEGFR-2/NRP specific signaling
por: Toivanen, Pyry I., et al.
Publicado: (2017)

Development of Large-Scale Downstream Processing for Lentiviral Vectors
por: Valkama, Anniina J., et al.
Publicado: (2020)

Optimization of lentiviral vector production for scale-up in fixed-bed bioreactor
por: Valkama, A J, et al.
Publicado: (2018)

Serum angiopoietin-2 and soluble VEGFR-2 levels predict malignancy of ovarian neoplasm and poor prognosis in epithelial ovarian cancer
por: Sallinen, Hanna, et al.
Publicado: (2014)

Gamma-Secretase Inhibitor Treatment Promotes VEGF-A-Driven Blood Vessel Growth and Vascular Leakage but Disrupts Neovascular Perfusion
por: Kalén, Mattias, et al.
Publicado: (2011)

Characterization of a new IN-I-PpoI fusion protein and a homology-arm containing transgene cassette that improve transgene expression persistence and 28S rRNA gene-targeted insertion of lentiviral vectors
por: Nousiainen, Alisa, et al.
Publicado: (2023)

Lipid accumulation, lipid oxidation, and low plasma levels of acquired antibodies against oxidized lipids associate with degeneration and rupture of the intracranial aneurysm wall
por: Frösen, Juhana, et al.
Publicado: (2013)

Lentiviral Protein Transduction with Genome-Modifying HIV-1 Integrase-I-PpoI Fusion Proteins: Studies on Specificity and Cytotoxicity
por: Turkki, Vesa, et al.
Publicado: (2014)

Interferon gene therapy with nadofaragene firadenovec for bladder cancer: from bench to approval
por: Martini, Alberto, et al.
Publicado: (2023)

Specific micro-RNA expression patterns distinguish the basal and luminal subtypes of muscle-invasive bladder cancer
por: Ochoa, Andrea E., et al.
Publicado: (2016)

Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells
por: Zhu, Keyi, et al.
Publicado: (2009)

Human Vascular Endothelial Growth Factor A(165) Expression Induces the Mouse Model of Neovascular Age-Related Macular Degeneration
por: Kokki, Emmi, et al.
Publicado: (2018)

Novel Designed Proteolytically Resistant VEGF-B186R127S Promotes Angiogenesis in Mouse Heart by Recruiting Endothelial Progenitor Cells
por: Mallick, Rahul, et al.
Publicado: (2022)

Gene Therapy Used in Cancer Treatment
por: Wirth, Thomas, et al.
Publicado: (2014)

Therapeutic Potential of VEGF-B in Coronary Heart Disease and Heart Failure: Dream or Vision?
por: Mallick, Rahul, et al.
Publicado: (2022)

Preclinical Proof-of-Concept, Analytical Development, and Commercial Scale Production of Lentiviral Vector in Adherent Cells
por: Leinonen, Hanna M., et al.
Publicado: (2019)

Intrinsic subtypes and bladder cancer metastasis
por: McConkey, David J., et al.
Publicado: (2016)

Lymphatic insufficiency leads to distinct myocardial infarct content assessed by magnetic resonance T(RAFFn), T(1ρ) and T(2) relaxation times
por: Ylä-Herttuala, Elias, et al.
Publicado: (2023)

Downregulation of VEGFR3 signaling alters cardiac lymphatic vessel organization and leads to a higher mortality after acute myocardial infarction
por: Vuorio, Taina, et al.
Publicado: (2018)

Long Non-Coding RNA Modulation of VEGF-A during Hypoxia
por: Nieminen, Tiina, et al.
Publicado: (2018)

Promoting blood vessel growth in ischemic diseases: challenges in translating preclinical potential into clinical success
por: Dragneva, Galina, et al.
Publicado: (2013)

Dotted collar placed around carotid artery induces asymmetric neointimal lesion formation in rabbits without intravascular manipulations
por: Kivelä, Antti, et al.
Publicado: (2012)

Adenoviral intramyocardial VEGF-D(ΔNΔC) gene transfer increases myocardial perfusion reserve in refractory angina patients: a phase I/IIa study with 1-year follow-up
por: Hartikainen, Juha, et al.
Publicado: (2017)

Adenoviral Gene Therapy Vectors in Clinical Use—Basic Aspects with a Special Reference to Replication-Competent Adenovirus Formation and Its Impact on Clinical Safety
por: Leikas, Aleksi J., et al.
Publicado: (2023)

A New Gene Therapy Approach for Cardiovascular Disease by Non-coding RNAs Acting in the Nucleus
por: Husso, Tiia, et al.
Publicado: (2014)

Nucleic Acid–Based Therapies for Atherosclerosis
por: Mäkinen, Petri, et al.
Publicado: (2020)

Novel RNAi-Based Therapies for Atherosclerosis
por: Ruotsalainen, Anna-Kaisa, et al.
Publicado: (2021)

A multipurpose vector system for the screening of libraries in bacteria, insect and mammalian cells and expression in vivo
por: Laitinen, Olli H., et al.
Publicado: (2005)

Fibroblast Growth Factor Receptors-1 and -3 Play Distinct Roles in the Regulation of Bladder Cancer Growth and Metastasis: Implications for Therapeutic Targeting
por: Cheng, Tiewei, et al.
Publicado: (2013)

In-Frame cDNA Library Combined with Protein Complementation Assay Identifies ARL11-Binding Partners
por: Lee, Sangkyou, et al.
Publicado: (2012)

Viral-Vector-Delivered Anti-Angiogenic Therapies to the Eye
por: Koponen, Sanna, et al.
Publicado: (2021)

Epigenetic Regulation of Vascular Smooth Muscle Cell Phenotype Switching in Atherosclerotic Artery Remodeling: A Mini-Review
por: Zurek, Michelle, et al.
Publicado: (2021)

The deubiquitinase Otub1 controls the activation of CD8 T cells and NK cells by regulating IL-15-mediated priming
por: Zhou, Xiaofei, et al.
Publicado: (2019)

Differential Regulation of Vascular Endothelial Growth Factors by Promoter-targeted shRNAs
por: Laham-Karam, Nihay, et al.
Publicado: (2015)

Editorial: Vascularization for Regenerative Medicine
por: Banfi, Andrea, et al.
Publicado: (2018)

Experimental Evaluation of an Interferometric Light Microscopy Particle Counter for Titering and Characterization of Virus Preparations
por: Turkki, Vesa, et al.
Publicado: (2021)

Employing an orthotopic model to study the role of epithelial-mesenchymal transition in bladder cancer metastasis
por: Roth, Beat, et al.
Publicado: (2016)

Inhibition of Inducible Heat Shock Protein-70 (Hsp72) Enhances Bortezomib-Induced Cell Death in Human Bladder Cancer Cells
por: Qi, Wei, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_7sf9iphg50j2krjgufrfp0ojbm