Sensitive detection of stage I lung adenocarcinoma using plasma cell-free DNA breakpoint motif profiling

BACKGROUND: Early diagnosis benefits lung cancer patients with higher survival, but most patients are diagnosed after metastasis. Although cell-free DNA (cfDNA) analysis holds promise, its sensitivity for detecting early-stage lung cancer is unsatisfying. We leveraged cfDNA fragmentomics to develop...

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Detalles Bibliográficos
Autores principales: Guo, Wei, Chen, Xin, Liu, Rui, Liang, Naixin, Ma, Qianli, Bao, Hua, Xu, Xiuxiu, Wu, Xue, Yang, Shanshan, Shao, Yang, Tan, Fengwei, Xue, Qi, Gao, Shugeng, He, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251329/
https://www.ncbi.nlm.nih.gov/pubmed/35780566
http://dx.doi.org/10.1016/j.ebiom.2022.104131

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