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Complete Spontaneous Regression of Squamous-Cell Lung Cancer: A Case Report
Spontaneous regression of cancer is an extremely rare phenomenon, and it has been described in only a few cases of pulmonary cancer. We report a case of complete spontaneous regression of squamous-cell lung cancer (SCLC) following a core needle biopsy in a 67-year-old female patient with two previou...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251478/ https://www.ncbi.nlm.nih.gov/pubmed/35949899 http://dx.doi.org/10.1159/000525058 |
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author | Klitgaard, Allan Løkke, Anders Lager, Jakob Rasmussen, Torben Riis Hilberg, Ole |
author_facet | Klitgaard, Allan Løkke, Anders Lager, Jakob Rasmussen, Torben Riis Hilberg, Ole |
author_sort | Klitgaard, Allan |
collection | PubMed |
description | Spontaneous regression of cancer is an extremely rare phenomenon, and it has been described in only a few cases of pulmonary cancer. We report a case of complete spontaneous regression of squamous-cell lung cancer (SCLC) following a core needle biopsy in a 67-year-old female patient with two previous lung cancers and concomitant follicular lymphoma. The patient was diagnosed with SCLC after 4 core needle biopsies from a nodule in the left upper lobe and at the same time suspected of having follicular lymphoma. Treatment for the lung cancer was delayed by approximately 8 weeks because the diagnosis of lymphoma was both challenging and time-consuming. A computed tomography scan was performed in relation to the scheduled treatment for SCLC, showing that the pulmonary nodule had disappeared completely. Most other cases of spontaneous regression of lung cancer hint at the involvement of immunological factors, and this case possibly involves a combination of mechanical and local immunological factors. Genetic and immunological analysis of patients showing spontaneous regression of cancers could provide valuable information. |
format | Online Article Text |
id | pubmed-9251478 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-92514782022-08-09 Complete Spontaneous Regression of Squamous-Cell Lung Cancer: A Case Report Klitgaard, Allan Løkke, Anders Lager, Jakob Rasmussen, Torben Riis Hilberg, Ole Case Rep Oncol Case Report Spontaneous regression of cancer is an extremely rare phenomenon, and it has been described in only a few cases of pulmonary cancer. We report a case of complete spontaneous regression of squamous-cell lung cancer (SCLC) following a core needle biopsy in a 67-year-old female patient with two previous lung cancers and concomitant follicular lymphoma. The patient was diagnosed with SCLC after 4 core needle biopsies from a nodule in the left upper lobe and at the same time suspected of having follicular lymphoma. Treatment for the lung cancer was delayed by approximately 8 weeks because the diagnosis of lymphoma was both challenging and time-consuming. A computed tomography scan was performed in relation to the scheduled treatment for SCLC, showing that the pulmonary nodule had disappeared completely. Most other cases of spontaneous regression of lung cancer hint at the involvement of immunological factors, and this case possibly involves a combination of mechanical and local immunological factors. Genetic and immunological analysis of patients showing spontaneous regression of cancers could provide valuable information. S. Karger AG 2022-06-17 /pmc/articles/PMC9251478/ /pubmed/35949899 http://dx.doi.org/10.1159/000525058 Text en Copyright © 2022 by The Author(s). Published by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission. |
spellingShingle | Case Report Klitgaard, Allan Løkke, Anders Lager, Jakob Rasmussen, Torben Riis Hilberg, Ole Complete Spontaneous Regression of Squamous-Cell Lung Cancer: A Case Report |
title | Complete Spontaneous Regression of Squamous-Cell Lung Cancer: A Case Report |
title_full | Complete Spontaneous Regression of Squamous-Cell Lung Cancer: A Case Report |
title_fullStr | Complete Spontaneous Regression of Squamous-Cell Lung Cancer: A Case Report |
title_full_unstemmed | Complete Spontaneous Regression of Squamous-Cell Lung Cancer: A Case Report |
title_short | Complete Spontaneous Regression of Squamous-Cell Lung Cancer: A Case Report |
title_sort | complete spontaneous regression of squamous-cell lung cancer: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251478/ https://www.ncbi.nlm.nih.gov/pubmed/35949899 http://dx.doi.org/10.1159/000525058 |
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