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Global metabolic alterations in colorectal cancer cells during irinotecan-induced DNA replication stress
BACKGROUND: Metabolic adaptations can allow cancer cells to survive DNA-damaging chemotherapy. This unmet clinical challenge is a potential vulnerability of cancer. Accordingly, there is an intense search for mechanisms that modulate cell metabolism during anti-tumor therapy. We set out to define ho...
Autores principales: | Marx, Christian, Sonnemann, Jürgen, Maddocks, Oliver D. K., Marx-Blümel, Lisa, Beyer, Mandy, Hoelzer, Doerte, Thierbach, René, Maletzki, Claudia, Linnebacher, Michael, Heinzel, Thorsten, Krämer, Oliver H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251592/ https://www.ncbi.nlm.nih.gov/pubmed/35787728 http://dx.doi.org/10.1186/s40170-022-00286-9 |
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