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Extracellular vesicles from bone mesenchymal stem cells transport microRNA-206 into osteosarcoma cells and target NRSN2 to block the ERK1/2-Bcl-xL signaling pathway

Osteosarcoma (OS) is a kind of malignant tumor originating from mesenchymal tissues. Bone mesenchymal stem cells-derived extracellular vesicles (BMSCs-EVs) can play important roles in OS. This study investigated the mechanism of BMSCs-EVs on OS. BMSC surface antigens and adipogenic and osteogenic di...

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Detalles Bibliográficos
Autores principales: Keremu, Alimu, Aila, Pazila, Tusun, Aikebaier, Abulikemu, Maimaitiaili, Zou, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251612/
https://www.ncbi.nlm.nih.gov/pubmed/35730574
http://dx.doi.org/10.4081/ejh.2022.3394

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