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Inhibition of HMGB1 suppresses inflammation and catabolism in temporomandibular joint osteoarthritis via NF-κB signaling pathway

HMGB1 is a highly conserved nuclear protein that is rapidly released into the extracellular environment during infection or tissue damage. In osteoarthritis, HMGB1 acts as a pro-inflammatory cytokine inducing a positive feedback loop for synovial inflammation and cartilage degradation. The aim of th...

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Detalles Bibliográficos
Autores principales:	Li, Yan Yan, Feng, Ya Ping, Liu, Li, Ke, Jin, Long, Xing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PAGEPress Publications, Pavia, Italy 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251613/ https://www.ncbi.nlm.nih.gov/pubmed/35726537 http://dx.doi.org/10.4081/ejh.2022.3357

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