Prior Pulmonary Tuberculosis Is a Risk Factor for Asymptomatic Cryptococcal Antigenemia in a Cohort of Adults With Advanced Human Immunodeficiency Virus Disease

The greater mortality risk among people with advanced human immunodeficiency virus disease and cryptococcal antigenemia, despite treatment, indicates an increased susceptibility to other infections. We found that prior tuberculosis was an independent risk factor for cryptococcal antigenemia (adjuste...

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Autores principales: Wake, Rachel M, Ismail, Nazir A, Omar, Shaheed V, Ismail, Farzana, Tiemessen, Caroline T, Harrison, Thomas S, Jarvis, Joseph N, Govender, Nelesh P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251663/
https://www.ncbi.nlm.nih.gov/pubmed/35794929
http://dx.doi.org/10.1093/ofid/ofac202
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author Wake, Rachel M
Ismail, Nazir A
Omar, Shaheed V
Ismail, Farzana
Tiemessen, Caroline T
Harrison, Thomas S
Jarvis, Joseph N
Govender, Nelesh P
author_facet Wake, Rachel M
Ismail, Nazir A
Omar, Shaheed V
Ismail, Farzana
Tiemessen, Caroline T
Harrison, Thomas S
Jarvis, Joseph N
Govender, Nelesh P
author_sort Wake, Rachel M
collection PubMed
description The greater mortality risk among people with advanced human immunodeficiency virus disease and cryptococcal antigenemia, despite treatment, indicates an increased susceptibility to other infections. We found that prior tuberculosis was an independent risk factor for cryptococcal antigenemia (adjusted odds ratio, 2.72; 95% confidence interval, 1.13–6.52; P = .03) among patients with CD4 counts <100 cells/µL.
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spelling pubmed-92516632022-07-05 Prior Pulmonary Tuberculosis Is a Risk Factor for Asymptomatic Cryptococcal Antigenemia in a Cohort of Adults With Advanced Human Immunodeficiency Virus Disease Wake, Rachel M Ismail, Nazir A Omar, Shaheed V Ismail, Farzana Tiemessen, Caroline T Harrison, Thomas S Jarvis, Joseph N Govender, Nelesh P Open Forum Infect Dis Brief Report The greater mortality risk among people with advanced human immunodeficiency virus disease and cryptococcal antigenemia, despite treatment, indicates an increased susceptibility to other infections. We found that prior tuberculosis was an independent risk factor for cryptococcal antigenemia (adjusted odds ratio, 2.72; 95% confidence interval, 1.13–6.52; P = .03) among patients with CD4 counts <100 cells/µL. Oxford University Press 2022-04-17 /pmc/articles/PMC9251663/ /pubmed/35794929 http://dx.doi.org/10.1093/ofid/ofac202 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Wake, Rachel M
Ismail, Nazir A
Omar, Shaheed V
Ismail, Farzana
Tiemessen, Caroline T
Harrison, Thomas S
Jarvis, Joseph N
Govender, Nelesh P
Prior Pulmonary Tuberculosis Is a Risk Factor for Asymptomatic Cryptococcal Antigenemia in a Cohort of Adults With Advanced Human Immunodeficiency Virus Disease
title Prior Pulmonary Tuberculosis Is a Risk Factor for Asymptomatic Cryptococcal Antigenemia in a Cohort of Adults With Advanced Human Immunodeficiency Virus Disease
title_full Prior Pulmonary Tuberculosis Is a Risk Factor for Asymptomatic Cryptococcal Antigenemia in a Cohort of Adults With Advanced Human Immunodeficiency Virus Disease
title_fullStr Prior Pulmonary Tuberculosis Is a Risk Factor for Asymptomatic Cryptococcal Antigenemia in a Cohort of Adults With Advanced Human Immunodeficiency Virus Disease
title_full_unstemmed Prior Pulmonary Tuberculosis Is a Risk Factor for Asymptomatic Cryptococcal Antigenemia in a Cohort of Adults With Advanced Human Immunodeficiency Virus Disease
title_short Prior Pulmonary Tuberculosis Is a Risk Factor for Asymptomatic Cryptococcal Antigenemia in a Cohort of Adults With Advanced Human Immunodeficiency Virus Disease
title_sort prior pulmonary tuberculosis is a risk factor for asymptomatic cryptococcal antigenemia in a cohort of adults with advanced human immunodeficiency virus disease
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251663/
https://www.ncbi.nlm.nih.gov/pubmed/35794929
http://dx.doi.org/10.1093/ofid/ofac202
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