Transcription factor GATA2 may potentiate follicle-stimulating hormone production in mice via induction of the BMP antagonist gremlin in gonadotrope cells

Mammalian reproduction depends on the gonadotropins, follicle-stimulating hormone (FSH), and luteinizing hormone, which are secreted by pituitary gonadotrope cells. The zinc-finger transcription factor GATA2 was previously implicated in FSH production in male mice; however, its mechanisms of action...

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Detalles Bibliográficos
Autores principales: Schang, Gauthier, Ongaro, Luisina, Brûlé, Emilie, Zhou, Xiang, Wang, Ying, Boehm, Ulrich, Ruf-Zamojski, Frederique, Zamojski, Michel, Mendelev, Natalia, Seenarine, Nitish, Amper, Mary Anne, Nair, Venugopalan, Ge, Yongchao, Sealfon, Stuart C., Bernard, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251782/
https://www.ncbi.nlm.nih.gov/pubmed/35643321
http://dx.doi.org/10.1016/j.jbc.2022.102072

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