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The FLT3 Y842D mutation may be highly sensitive to midostaurin: a case report

A Y842D mutation within the activation loop of fms-like tyrosine kinase 3 (FLT3) has been shown to confer strong resistance to sorafenib in vitro. Whether this type of mutation exerts clinically significant effects in patients with acute myeloid leukaemia (AML) remains unclear. Here, a novel Y842D a...

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Detalles Bibliográficos
Autores principales:	He, Shujiao, Zhang, Minjie, Li, Jieying, Zhao, Weiqiang, Yu, Li, Han, Ying, Pang, Yanbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2022
Materias:	Case Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251825/ https://www.ncbi.nlm.nih.gov/pubmed/35549749 http://dx.doi.org/10.1177/03000605221097774

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