Cargando…
Gastric stem cells promote inflammation and gland remodeling in response to Helicobacter pylori via Rspo3‐Lgr4 axis
Helicobacter pylori is a pathogen that colonizes the stomach and causes chronic gastritis. Helicobacter pylori can colonize deep inside gastric glands, triggering increased R‐spondin 3 (Rspo3) signaling. This causes an expansion of the “gland base module,” which consists of self‐renewing stem cells...
Autores principales: | Wizenty, Jonas, Müllerke, Stefanie, Kolesnichenko, Marina, Heuberger, Julian, Lin, Manqiang, Fischer, Anne‐Sophie, Mollenkopf, Hans‐Joachim, Berger, Hilmar, Tacke, Frank, Sigal, Michael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251867/ https://www.ncbi.nlm.nih.gov/pubmed/35767364 http://dx.doi.org/10.15252/embj.2021109996 |
Ejemplares similares
-
R-spondin/YAP axis promotes gastric oxyntic gland regeneration and Helicobacter pylori–associated metaplasia in mice
por: Fischer, Anne-Sophie, et al.
Publicado: (2022) -
Responses of gastric epithelial stem cells and their niche to Helicobacter pylori infection
por: Wizenty, Jonas, et al.
Publicado: (2020) -
BMP feed-forward loop promotes terminal differentiation in gastric glands and is interrupted by H. pylori-driven inflammation
por: Kapalczynska, Marta, et al.
Publicado: (2022) -
Association of Helicobacter pylori Positivity With Risk of Disease and Mortality
por: Wizenty, Jonas, et al.
Publicado: (2023) -
Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche
por: Lin, Manqiang, et al.
Publicado: (2023)