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The obesity paradox for survivors of critically ill patients

The obesity paradox has been observed in short-term outcomes from critical illness. However, little is known regarding the impact of obesity on long-term outcomes for survivors of critically ill patients. We aimed to evaluate the influence of obesity on long-term mortality outcomes after discharge a...

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Autores principales: Zhou, Dawei, Wang, Chao, Lin, Qing, Li, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251913/
https://www.ncbi.nlm.nih.gov/pubmed/35781349
http://dx.doi.org/10.1186/s13054-022-04074-1
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author Zhou, Dawei
Wang, Chao
Lin, Qing
Li, Tong
author_facet Zhou, Dawei
Wang, Chao
Lin, Qing
Li, Tong
author_sort Zhou, Dawei
collection PubMed
description The obesity paradox has been observed in short-term outcomes from critical illness. However, little is known regarding the impact of obesity on long-term outcomes for survivors of critically ill patients. We aimed to evaluate the influence of obesity on long-term mortality outcomes after discharge alive from ICU. The adult patients who were discharged alive from the last ICU admission were extracted. After exclusion, a total of 7619 adult patients discharged alive from ICU were included, with 4-year mortality of 32%. The median body mass index (BMI) was 27.2 (IQR 24–31.4) kg/m(2), and 2490 (31.5%) patients were classified as obese or morbidly obese. The morbidly obese patients had the highest ICU and hospital length of stay. However, higher BMI was associated with lower hazard ratio for 4-year mortality. The results showed the obesity paradox may be also suitable for survivors of critically ill patients.
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spelling pubmed-92519132022-07-05 The obesity paradox for survivors of critically ill patients Zhou, Dawei Wang, Chao Lin, Qing Li, Tong Crit Care Brief Report The obesity paradox has been observed in short-term outcomes from critical illness. However, little is known regarding the impact of obesity on long-term outcomes for survivors of critically ill patients. We aimed to evaluate the influence of obesity on long-term mortality outcomes after discharge alive from ICU. The adult patients who were discharged alive from the last ICU admission were extracted. After exclusion, a total of 7619 adult patients discharged alive from ICU were included, with 4-year mortality of 32%. The median body mass index (BMI) was 27.2 (IQR 24–31.4) kg/m(2), and 2490 (31.5%) patients were classified as obese or morbidly obese. The morbidly obese patients had the highest ICU and hospital length of stay. However, higher BMI was associated with lower hazard ratio for 4-year mortality. The results showed the obesity paradox may be also suitable for survivors of critically ill patients. BioMed Central 2022-07-03 /pmc/articles/PMC9251913/ /pubmed/35781349 http://dx.doi.org/10.1186/s13054-022-04074-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Brief Report
Zhou, Dawei
Wang, Chao
Lin, Qing
Li, Tong
The obesity paradox for survivors of critically ill patients
title The obesity paradox for survivors of critically ill patients
title_full The obesity paradox for survivors of critically ill patients
title_fullStr The obesity paradox for survivors of critically ill patients
title_full_unstemmed The obesity paradox for survivors of critically ill patients
title_short The obesity paradox for survivors of critically ill patients
title_sort obesity paradox for survivors of critically ill patients
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251913/
https://www.ncbi.nlm.nih.gov/pubmed/35781349
http://dx.doi.org/10.1186/s13054-022-04074-1
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