Nociceptive signaling through transient receptor potential vanilloid 1 is regulated by Cyclin Dependent Kinase 5-mediated phosphorylation of T407 in vivo

Cyclin dependent kinase 5 (Cdk5) is a key neuronal kinase whose activity can modulate thermo-, mechano-, and chemo-nociception. Cdk5 can modulate nociceptor firing by phosphorylating pain transducing ion channels like the transient receptor potential vanilloid 1 (TRPV1), a thermoreceptor that is act...

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Detalles Bibliográficos
Autores principales: Cho, Andrew, Hall, Bradford E, Limaye, Advait S, Wang, Sheng, Chung, Man-Kyo, Kulkarni, Ashok B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251968/
https://www.ncbi.nlm.nih.gov/pubmed/35726573
http://dx.doi.org/10.1177/17448069221111473

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