Cargando…
Contemporary outcomes of cardiac surgery patients supported by the intra-aortic balloon pump
OBJECTIVES: Although the intra-aortic balloon pump (IABP) has been the most widely adopted temporary mechanical support device in cardiac surgical patients, its use has declined. The current study aimed to evaluate the occurrence and predictors of early mortality and complication rates in contempora...
Autores principales: | , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252119/ https://www.ncbi.nlm.nih.gov/pubmed/35381083 http://dx.doi.org/10.1093/icvts/ivac091 |
_version_ | 1784740193009401856 |
---|---|
author | Lorusso, Roberto Heuts, Samuel Jiritano, Federica Scrofani, Roberto Antona, Carlo Actis Dato, Guglielmo Centofanti, Paolo Ferrarese, Sandro Matteucci, Matteo Miceli, Antonio Glauber, Mattia Vizzardi, Enrico Sponga, Sandro Vendramin, Igor Garatti, Andrea de Vincentis, Carlo De Bonis, Michele Ajello, Silvia Troise, Giovanni Dalla Tomba, Margherita Serraino, Filiberto |
author_facet | Lorusso, Roberto Heuts, Samuel Jiritano, Federica Scrofani, Roberto Antona, Carlo Actis Dato, Guglielmo Centofanti, Paolo Ferrarese, Sandro Matteucci, Matteo Miceli, Antonio Glauber, Mattia Vizzardi, Enrico Sponga, Sandro Vendramin, Igor Garatti, Andrea de Vincentis, Carlo De Bonis, Michele Ajello, Silvia Troise, Giovanni Dalla Tomba, Margherita Serraino, Filiberto |
author_sort | Lorusso, Roberto |
collection | PubMed |
description | OBJECTIVES: Although the intra-aortic balloon pump (IABP) has been the most widely adopted temporary mechanical support device in cardiac surgical patients, its use has declined. The current study aimed to evaluate the occurrence and predictors of early mortality and complication rates in contemporary cardiac surgery patients supported by an IABP. METHODS: A multicentre, retrospective analysis was performed of all consecutive cardiac surgical patients receiving perioperative balloon pump support in 8 centres between January 2010 to December 2019. The primary outcome was early mortality, and secondary outcomes were balloon-associated complications. A multivariable binary logistic regression model was applied to evaluate predictors of the primary outcome. RESULTS: The study cohort consisted of 2615 consecutive patients. The median age was 68 years [25th percentile 61, 75th percentile 75 years], with the majority being male (76.9%), and a mean calculated 30-day mortality risk of 10.0%. Early mortality was 12.7% (n = 333), due to cardiac causes (n = 266), neurological causes (=22), balloon-related causes (n = 5) and other causes (n = 40). A composite end point of all vascular complications occurred in 7.2% of patients, and leg ischaemia was observed in 1.3% of patients. The most important predictors of early mortality were peripheral vascular disease [odds ratio (OR) 1.63], postoperative dialysis requirement (OR 10.40) and vascular complications (OR 2.57). CONCLUSIONS: The use of the perioperative IABP proved to be safe and demonstrated relatively low complication rates, particularly for leg ischaemia. As such, we believe that specialists should not be held back to use this widely available treatment in high-risk cardiac surgical patients when indicated. |
format | Online Article Text |
id | pubmed-9252119 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-92521192022-07-05 Contemporary outcomes of cardiac surgery patients supported by the intra-aortic balloon pump Lorusso, Roberto Heuts, Samuel Jiritano, Federica Scrofani, Roberto Antona, Carlo Actis Dato, Guglielmo Centofanti, Paolo Ferrarese, Sandro Matteucci, Matteo Miceli, Antonio Glauber, Mattia Vizzardi, Enrico Sponga, Sandro Vendramin, Igor Garatti, Andrea de Vincentis, Carlo De Bonis, Michele Ajello, Silvia Troise, Giovanni Dalla Tomba, Margherita Serraino, Filiberto Interact Cardiovasc Thorac Surg Adult Cardiac OBJECTIVES: Although the intra-aortic balloon pump (IABP) has been the most widely adopted temporary mechanical support device in cardiac surgical patients, its use has declined. The current study aimed to evaluate the occurrence and predictors of early mortality and complication rates in contemporary cardiac surgery patients supported by an IABP. METHODS: A multicentre, retrospective analysis was performed of all consecutive cardiac surgical patients receiving perioperative balloon pump support in 8 centres between January 2010 to December 2019. The primary outcome was early mortality, and secondary outcomes were balloon-associated complications. A multivariable binary logistic regression model was applied to evaluate predictors of the primary outcome. RESULTS: The study cohort consisted of 2615 consecutive patients. The median age was 68 years [25th percentile 61, 75th percentile 75 years], with the majority being male (76.9%), and a mean calculated 30-day mortality risk of 10.0%. Early mortality was 12.7% (n = 333), due to cardiac causes (n = 266), neurological causes (=22), balloon-related causes (n = 5) and other causes (n = 40). A composite end point of all vascular complications occurred in 7.2% of patients, and leg ischaemia was observed in 1.3% of patients. The most important predictors of early mortality were peripheral vascular disease [odds ratio (OR) 1.63], postoperative dialysis requirement (OR 10.40) and vascular complications (OR 2.57). CONCLUSIONS: The use of the perioperative IABP proved to be safe and demonstrated relatively low complication rates, particularly for leg ischaemia. As such, we believe that specialists should not be held back to use this widely available treatment in high-risk cardiac surgical patients when indicated. Oxford University Press 2022-04-05 /pmc/articles/PMC9252119/ /pubmed/35381083 http://dx.doi.org/10.1093/icvts/ivac091 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Adult Cardiac Lorusso, Roberto Heuts, Samuel Jiritano, Federica Scrofani, Roberto Antona, Carlo Actis Dato, Guglielmo Centofanti, Paolo Ferrarese, Sandro Matteucci, Matteo Miceli, Antonio Glauber, Mattia Vizzardi, Enrico Sponga, Sandro Vendramin, Igor Garatti, Andrea de Vincentis, Carlo De Bonis, Michele Ajello, Silvia Troise, Giovanni Dalla Tomba, Margherita Serraino, Filiberto Contemporary outcomes of cardiac surgery patients supported by the intra-aortic balloon pump |
title | Contemporary outcomes of cardiac surgery patients supported by the intra-aortic balloon pump |
title_full | Contemporary outcomes of cardiac surgery patients supported by the intra-aortic balloon pump |
title_fullStr | Contemporary outcomes of cardiac surgery patients supported by the intra-aortic balloon pump |
title_full_unstemmed | Contemporary outcomes of cardiac surgery patients supported by the intra-aortic balloon pump |
title_short | Contemporary outcomes of cardiac surgery patients supported by the intra-aortic balloon pump |
title_sort | contemporary outcomes of cardiac surgery patients supported by the intra-aortic balloon pump |
topic | Adult Cardiac |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252119/ https://www.ncbi.nlm.nih.gov/pubmed/35381083 http://dx.doi.org/10.1093/icvts/ivac091 |
work_keys_str_mv | AT lorussoroberto contemporaryoutcomesofcardiacsurgerypatientssupportedbytheintraaorticballoonpump AT heutssamuel contemporaryoutcomesofcardiacsurgerypatientssupportedbytheintraaorticballoonpump AT jiritanofederica contemporaryoutcomesofcardiacsurgerypatientssupportedbytheintraaorticballoonpump AT scrofaniroberto contemporaryoutcomesofcardiacsurgerypatientssupportedbytheintraaorticballoonpump AT antonacarlo contemporaryoutcomesofcardiacsurgerypatientssupportedbytheintraaorticballoonpump AT actisdatoguglielmo contemporaryoutcomesofcardiacsurgerypatientssupportedbytheintraaorticballoonpump AT centofantipaolo contemporaryoutcomesofcardiacsurgerypatientssupportedbytheintraaorticballoonpump AT ferraresesandro contemporaryoutcomesofcardiacsurgerypatientssupportedbytheintraaorticballoonpump AT matteuccimatteo contemporaryoutcomesofcardiacsurgerypatientssupportedbytheintraaorticballoonpump AT miceliantonio contemporaryoutcomesofcardiacsurgerypatientssupportedbytheintraaorticballoonpump AT glaubermattia contemporaryoutcomesofcardiacsurgerypatientssupportedbytheintraaorticballoonpump AT vizzardienrico contemporaryoutcomesofcardiacsurgerypatientssupportedbytheintraaorticballoonpump AT spongasandro contemporaryoutcomesofcardiacsurgerypatientssupportedbytheintraaorticballoonpump AT vendraminigor contemporaryoutcomesofcardiacsurgerypatientssupportedbytheintraaorticballoonpump AT garattiandrea contemporaryoutcomesofcardiacsurgerypatientssupportedbytheintraaorticballoonpump AT devincentiscarlo contemporaryoutcomesofcardiacsurgerypatientssupportedbytheintraaorticballoonpump AT debonismichele contemporaryoutcomesofcardiacsurgerypatientssupportedbytheintraaorticballoonpump AT ajellosilvia contemporaryoutcomesofcardiacsurgerypatientssupportedbytheintraaorticballoonpump AT troisegiovanni contemporaryoutcomesofcardiacsurgerypatientssupportedbytheintraaorticballoonpump AT dallatombamargherita contemporaryoutcomesofcardiacsurgerypatientssupportedbytheintraaorticballoonpump AT serrainofiliberto contemporaryoutcomesofcardiacsurgerypatientssupportedbytheintraaorticballoonpump |