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Contemporary outcomes of cardiac surgery patients supported by the intra-aortic balloon pump

OBJECTIVES: Although the intra-aortic balloon pump (IABP) has been the most widely adopted temporary mechanical support device in cardiac surgical patients, its use has declined. The current study aimed to evaluate the occurrence and predictors of early mortality and complication rates in contempora...

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Autores principales: Lorusso, Roberto, Heuts, Samuel, Jiritano, Federica, Scrofani, Roberto, Antona, Carlo, Actis Dato, Guglielmo, Centofanti, Paolo, Ferrarese, Sandro, Matteucci, Matteo, Miceli, Antonio, Glauber, Mattia, Vizzardi, Enrico, Sponga, Sandro, Vendramin, Igor, Garatti, Andrea, de Vincentis, Carlo, De Bonis, Michele, Ajello, Silvia, Troise, Giovanni, Dalla Tomba, Margherita, Serraino, Filiberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252119/
https://www.ncbi.nlm.nih.gov/pubmed/35381083
http://dx.doi.org/10.1093/icvts/ivac091
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author Lorusso, Roberto
Heuts, Samuel
Jiritano, Federica
Scrofani, Roberto
Antona, Carlo
Actis Dato, Guglielmo
Centofanti, Paolo
Ferrarese, Sandro
Matteucci, Matteo
Miceli, Antonio
Glauber, Mattia
Vizzardi, Enrico
Sponga, Sandro
Vendramin, Igor
Garatti, Andrea
de Vincentis, Carlo
De Bonis, Michele
Ajello, Silvia
Troise, Giovanni
Dalla Tomba, Margherita
Serraino, Filiberto
author_facet Lorusso, Roberto
Heuts, Samuel
Jiritano, Federica
Scrofani, Roberto
Antona, Carlo
Actis Dato, Guglielmo
Centofanti, Paolo
Ferrarese, Sandro
Matteucci, Matteo
Miceli, Antonio
Glauber, Mattia
Vizzardi, Enrico
Sponga, Sandro
Vendramin, Igor
Garatti, Andrea
de Vincentis, Carlo
De Bonis, Michele
Ajello, Silvia
Troise, Giovanni
Dalla Tomba, Margherita
Serraino, Filiberto
author_sort Lorusso, Roberto
collection PubMed
description OBJECTIVES: Although the intra-aortic balloon pump (IABP) has been the most widely adopted temporary mechanical support device in cardiac surgical patients, its use has declined. The current study aimed to evaluate the occurrence and predictors of early mortality and complication rates in contemporary cardiac surgery patients supported by an IABP. METHODS: A multicentre, retrospective analysis was performed of all consecutive cardiac surgical patients receiving perioperative balloon pump support in 8 centres between January 2010 to December 2019. The primary outcome was early mortality, and secondary outcomes were balloon-associated complications. A multivariable binary logistic regression model was applied to evaluate predictors of the primary outcome. RESULTS: The study cohort consisted of 2615 consecutive patients. The median age was 68 years [25th percentile 61, 75th percentile 75 years], with the majority being male (76.9%), and a mean calculated 30-day mortality risk of 10.0%. Early mortality was 12.7% (n = 333), due to cardiac causes (n = 266), neurological causes (=22), balloon-related causes (n = 5) and other causes (n = 40). A composite end point of all vascular complications occurred in 7.2% of patients, and leg ischaemia was observed in 1.3% of patients. The most important predictors of early mortality were peripheral vascular disease [odds ratio (OR) 1.63], postoperative dialysis requirement (OR 10.40) and vascular complications (OR 2.57). CONCLUSIONS: The use of the perioperative IABP proved to be safe and demonstrated relatively low complication rates, particularly for leg ischaemia. As such, we believe that specialists should not be held back to use this widely available treatment in high-risk cardiac surgical patients when indicated.
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spelling pubmed-92521192022-07-05 Contemporary outcomes of cardiac surgery patients supported by the intra-aortic balloon pump Lorusso, Roberto Heuts, Samuel Jiritano, Federica Scrofani, Roberto Antona, Carlo Actis Dato, Guglielmo Centofanti, Paolo Ferrarese, Sandro Matteucci, Matteo Miceli, Antonio Glauber, Mattia Vizzardi, Enrico Sponga, Sandro Vendramin, Igor Garatti, Andrea de Vincentis, Carlo De Bonis, Michele Ajello, Silvia Troise, Giovanni Dalla Tomba, Margherita Serraino, Filiberto Interact Cardiovasc Thorac Surg Adult Cardiac OBJECTIVES: Although the intra-aortic balloon pump (IABP) has been the most widely adopted temporary mechanical support device in cardiac surgical patients, its use has declined. The current study aimed to evaluate the occurrence and predictors of early mortality and complication rates in contemporary cardiac surgery patients supported by an IABP. METHODS: A multicentre, retrospective analysis was performed of all consecutive cardiac surgical patients receiving perioperative balloon pump support in 8 centres between January 2010 to December 2019. The primary outcome was early mortality, and secondary outcomes were balloon-associated complications. A multivariable binary logistic regression model was applied to evaluate predictors of the primary outcome. RESULTS: The study cohort consisted of 2615 consecutive patients. The median age was 68 years [25th percentile 61, 75th percentile 75 years], with the majority being male (76.9%), and a mean calculated 30-day mortality risk of 10.0%. Early mortality was 12.7% (n = 333), due to cardiac causes (n = 266), neurological causes (=22), balloon-related causes (n = 5) and other causes (n = 40). A composite end point of all vascular complications occurred in 7.2% of patients, and leg ischaemia was observed in 1.3% of patients. The most important predictors of early mortality were peripheral vascular disease [odds ratio (OR) 1.63], postoperative dialysis requirement (OR 10.40) and vascular complications (OR 2.57). CONCLUSIONS: The use of the perioperative IABP proved to be safe and demonstrated relatively low complication rates, particularly for leg ischaemia. As such, we believe that specialists should not be held back to use this widely available treatment in high-risk cardiac surgical patients when indicated. Oxford University Press 2022-04-05 /pmc/articles/PMC9252119/ /pubmed/35381083 http://dx.doi.org/10.1093/icvts/ivac091 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Adult Cardiac
Lorusso, Roberto
Heuts, Samuel
Jiritano, Federica
Scrofani, Roberto
Antona, Carlo
Actis Dato, Guglielmo
Centofanti, Paolo
Ferrarese, Sandro
Matteucci, Matteo
Miceli, Antonio
Glauber, Mattia
Vizzardi, Enrico
Sponga, Sandro
Vendramin, Igor
Garatti, Andrea
de Vincentis, Carlo
De Bonis, Michele
Ajello, Silvia
Troise, Giovanni
Dalla Tomba, Margherita
Serraino, Filiberto
Contemporary outcomes of cardiac surgery patients supported by the intra-aortic balloon pump
title Contemporary outcomes of cardiac surgery patients supported by the intra-aortic balloon pump
title_full Contemporary outcomes of cardiac surgery patients supported by the intra-aortic balloon pump
title_fullStr Contemporary outcomes of cardiac surgery patients supported by the intra-aortic balloon pump
title_full_unstemmed Contemporary outcomes of cardiac surgery patients supported by the intra-aortic balloon pump
title_short Contemporary outcomes of cardiac surgery patients supported by the intra-aortic balloon pump
title_sort contemporary outcomes of cardiac surgery patients supported by the intra-aortic balloon pump
topic Adult Cardiac
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252119/
https://www.ncbi.nlm.nih.gov/pubmed/35381083
http://dx.doi.org/10.1093/icvts/ivac091
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