Cargando…

Identification and Antibiotic Susceptibility of Eggerthella Lenta in Bloodstream Infections

The identification and antibiotic susceptibility of two clinical isolates of Eggerthella lenta from bloodstream infections were determined. This microorganism is rarely pathogenic, and the findings are presented here to promote the detection and awareness of this infection. The bacteria were obtaine...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xiangyun, Xu, Enjun, Shi, Cuixiao, Qiao, Guanhua, Chen, Shuyi, Xu, Yuanhong, Liu, Yajing, Bao, Xundi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252136/
https://www.ncbi.nlm.nih.gov/pubmed/35716165
http://dx.doi.org/10.33073/pjm-2022-024
_version_ 1784740197052710912
author Li, Xiangyun
Xu, Enjun
Shi, Cuixiao
Qiao, Guanhua
Chen, Shuyi
Xu, Yuanhong
Liu, Yajing
Bao, Xundi
author_facet Li, Xiangyun
Xu, Enjun
Shi, Cuixiao
Qiao, Guanhua
Chen, Shuyi
Xu, Yuanhong
Liu, Yajing
Bao, Xundi
author_sort Li, Xiangyun
collection PubMed
description The identification and antibiotic susceptibility of two clinical isolates of Eggerthella lenta from bloodstream infections were determined. This microorganism is rarely pathogenic, and the findings are presented here to promote the detection and awareness of this infection. The bacteria were obtained from one patient with pressure sores and another with a malignant gastric tumor. Smears were prepared, stained, and examined by microscopy. Single colonies were analyzed by Gram staining, MALDI-TOF MS, and the 16S rRNA gene sequencing. Antibiotic sensitivity was assessed by the agar dilution method. The bacilli were found to be Gram-positive, and the MS results showed 99.8% homology with E. lenta. It was confirmed by gene sequencing. Antibiotic susceptibility tests demonstrated that E. lenta was sensitive to piperacillin-tazobactam, ampicillin-sulbactam, imipenem, meropenem, metronidazole, clindamycin, and vancomycin. This study could increase awareness of this rare infection.
format Online
Article
Text
id pubmed-9252136
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Sciendo
record_format MEDLINE/PubMed
spelling pubmed-92521362022-07-18 Identification and Antibiotic Susceptibility of Eggerthella Lenta in Bloodstream Infections Li, Xiangyun Xu, Enjun Shi, Cuixiao Qiao, Guanhua Chen, Shuyi Xu, Yuanhong Liu, Yajing Bao, Xundi Pol J Microbiol Original Paper The identification and antibiotic susceptibility of two clinical isolates of Eggerthella lenta from bloodstream infections were determined. This microorganism is rarely pathogenic, and the findings are presented here to promote the detection and awareness of this infection. The bacteria were obtained from one patient with pressure sores and another with a malignant gastric tumor. Smears were prepared, stained, and examined by microscopy. Single colonies were analyzed by Gram staining, MALDI-TOF MS, and the 16S rRNA gene sequencing. Antibiotic sensitivity was assessed by the agar dilution method. The bacilli were found to be Gram-positive, and the MS results showed 99.8% homology with E. lenta. It was confirmed by gene sequencing. Antibiotic susceptibility tests demonstrated that E. lenta was sensitive to piperacillin-tazobactam, ampicillin-sulbactam, imipenem, meropenem, metronidazole, clindamycin, and vancomycin. This study could increase awareness of this rare infection. Sciendo 2022-06-19 /pmc/articles/PMC9252136/ /pubmed/35716165 http://dx.doi.org/10.33073/pjm-2022-024 Text en © 2022 Xiangyun Li et al., published by Sciendo https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
spellingShingle Original Paper
Li, Xiangyun
Xu, Enjun
Shi, Cuixiao
Qiao, Guanhua
Chen, Shuyi
Xu, Yuanhong
Liu, Yajing
Bao, Xundi
Identification and Antibiotic Susceptibility of Eggerthella Lenta in Bloodstream Infections
title Identification and Antibiotic Susceptibility of Eggerthella Lenta in Bloodstream Infections
title_full Identification and Antibiotic Susceptibility of Eggerthella Lenta in Bloodstream Infections
title_fullStr Identification and Antibiotic Susceptibility of Eggerthella Lenta in Bloodstream Infections
title_full_unstemmed Identification and Antibiotic Susceptibility of Eggerthella Lenta in Bloodstream Infections
title_short Identification and Antibiotic Susceptibility of Eggerthella Lenta in Bloodstream Infections
title_sort identification and antibiotic susceptibility of eggerthella lenta in bloodstream infections
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252136/
https://www.ncbi.nlm.nih.gov/pubmed/35716165
http://dx.doi.org/10.33073/pjm-2022-024
work_keys_str_mv AT lixiangyun identificationandantibioticsusceptibilityofeggerthellalentainbloodstreaminfections
AT xuenjun identificationandantibioticsusceptibilityofeggerthellalentainbloodstreaminfections
AT shicuixiao identificationandantibioticsusceptibilityofeggerthellalentainbloodstreaminfections
AT qiaoguanhua identificationandantibioticsusceptibilityofeggerthellalentainbloodstreaminfections
AT chenshuyi identificationandantibioticsusceptibilityofeggerthellalentainbloodstreaminfections
AT xuyuanhong identificationandantibioticsusceptibilityofeggerthellalentainbloodstreaminfections
AT liuyajing identificationandantibioticsusceptibilityofeggerthellalentainbloodstreaminfections
AT baoxundi identificationandantibioticsusceptibilityofeggerthellalentainbloodstreaminfections