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The L-shaped selection algorithm for multitrait genomic selection

Selecting for multiple traits as opposed to a single trait has become increasingly important in genomic selection. As one of the most popular approaches to multitrait genomic selection, index selection uses a weighted average of all traits as a single breeding objective. Although intuitive and effec...

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Autores principales: Amini, Fatemeh, Hu, Guiping, Wang, Lizhi, Wu, Ruoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252277/
https://www.ncbi.nlm.nih.gov/pubmed/35482523
http://dx.doi.org/10.1093/genetics/iyac069
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author Amini, Fatemeh
Hu, Guiping
Wang, Lizhi
Wu, Ruoyu
author_facet Amini, Fatemeh
Hu, Guiping
Wang, Lizhi
Wu, Ruoyu
author_sort Amini, Fatemeh
collection PubMed
description Selecting for multiple traits as opposed to a single trait has become increasingly important in genomic selection. As one of the most popular approaches to multitrait genomic selection, index selection uses a weighted average of all traits as a single breeding objective. Although intuitive and effective, index selection is not only numerically sensitive but also structurally incapable of finding certain optimal breeding parents. This paper proposes a new selection method for multitrait genomic selection, the L-shaped selection, which addresses the limitations of index selection by normalizing the trait values and using an L-shaped objective function to find optimal breeding parents. This algorithm has been proven to be able to find any Pareto optimal solution with appropriate weights. Two performance metrics have also been defined to quantify multitrait genomic selection algorithms with respect to their ability to accelerate genetic gain and preserve genetic diversity. Computational experiments were conducted to demonstrate the improved performance of L-shaped selection over-index selection.
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spelling pubmed-92522772022-12-16 The L-shaped selection algorithm for multitrait genomic selection Amini, Fatemeh Hu, Guiping Wang, Lizhi Wu, Ruoyu Genetics Investigation Selecting for multiple traits as opposed to a single trait has become increasingly important in genomic selection. As one of the most popular approaches to multitrait genomic selection, index selection uses a weighted average of all traits as a single breeding objective. Although intuitive and effective, index selection is not only numerically sensitive but also structurally incapable of finding certain optimal breeding parents. This paper proposes a new selection method for multitrait genomic selection, the L-shaped selection, which addresses the limitations of index selection by normalizing the trait values and using an L-shaped objective function to find optimal breeding parents. This algorithm has been proven to be able to find any Pareto optimal solution with appropriate weights. Two performance metrics have also been defined to quantify multitrait genomic selection algorithms with respect to their ability to accelerate genetic gain and preserve genetic diversity. Computational experiments were conducted to demonstrate the improved performance of L-shaped selection over-index selection. Oxford University Press 2022-04-28 /pmc/articles/PMC9252277/ /pubmed/35482523 http://dx.doi.org/10.1093/genetics/iyac069 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of Genetics Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Investigation
Amini, Fatemeh
Hu, Guiping
Wang, Lizhi
Wu, Ruoyu
The L-shaped selection algorithm for multitrait genomic selection
title The L-shaped selection algorithm for multitrait genomic selection
title_full The L-shaped selection algorithm for multitrait genomic selection
title_fullStr The L-shaped selection algorithm for multitrait genomic selection
title_full_unstemmed The L-shaped selection algorithm for multitrait genomic selection
title_short The L-shaped selection algorithm for multitrait genomic selection
title_sort l-shaped selection algorithm for multitrait genomic selection
topic Investigation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252277/
https://www.ncbi.nlm.nih.gov/pubmed/35482523
http://dx.doi.org/10.1093/genetics/iyac069
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