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Reconstruction of full-length LINE-1 progenitors from ancestral genomes
Sequences derived from the Long INterspersed Element-1 (L1) family of retrotransposons occupy at least 17% of the human genome, with 67 distinct subfamilies representing successive waves of expansion and extinction in mammalian lineages. L1s contribute extensively to gene regulation, but their molec...
Autores principales: | Campitelli, Laura F, Yellan, Isaac, Albu, Mihai, Barazandeh, Marjan, Patel, Zain M, Blanchette, Mathieu, Hughes, Timothy R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252281/ https://www.ncbi.nlm.nih.gov/pubmed/35552404 http://dx.doi.org/10.1093/genetics/iyac074 |
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