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Reconstruction of full-length LINE-1 progenitors from ancestral genomes

Sequences derived from the Long INterspersed Element-1 (L1) family of retrotransposons occupy at least 17% of the human genome, with 67 distinct subfamilies representing successive waves of expansion and extinction in mammalian lineages. L1s contribute extensively to gene regulation, but their molec...

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Detalles Bibliográficos
Autores principales:	Campitelli, Laura F, Yellan, Isaac, Albu, Mihai, Barazandeh, Marjan, Patel, Zain M, Blanchette, Mathieu, Hughes, Timothy R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252281/ https://www.ncbi.nlm.nih.gov/pubmed/35552404 http://dx.doi.org/10.1093/genetics/iyac074

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