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Candidate Proficiency Test Chemicals to Address Industrial Chemical Applicability Domains for in vitro Human Cytochrome P450 Enzyme Induction

Cytochrome P450 (CYP) enzymes play a key role in the metabolism of both xenobiotics and endogenous chemicals, and the activity of some CYP isoforms are susceptible to induction and/or inhibition by certain chemicals. As CYP induction/inhibition can bring about significant alterations in the level of...

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Detalles Bibliográficos
Autores principales:	Jacobs, Miriam Naomi, Kubickova, Barbara, Boshoff, Eugene
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Toxicology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252529/ https://www.ncbi.nlm.nih.gov/pubmed/35795225 http://dx.doi.org/10.3389/ftox.2022.880818

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