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Inhibition of Axitinib on Buspirone Metabolism in vitro and in vivo

OBJECTIVE: To evaluate the effect of axitinib on buspirone metabolism in vitro and in vivo. METHODS: A microsome incubation assay was performed to study the effect and mechanism of axitinib on buspirone metabolizing. In vivo, buspirone was administered with or without axitinib to Sprague–Dawley rats...

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Detalles Bibliográficos
Autores principales:	Zhang, Bo-Wen, Pang, Ni-Hong, Xu, Ren-Ai, Qu, Gao-Er, Tang, Cong-Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252588/ https://www.ncbi.nlm.nih.gov/pubmed/35795848 http://dx.doi.org/10.2147/DDDT.S359451

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