Pentosan Polysulfate Inhibits Attachment and Infection by SARS-CoV-2 In Vitro: Insights into Structural Requirements for Binding

Two years since the outbreak of the novel coronavirus SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) pandemic, there remain few clinically effective drugs to complement vaccines. One is the anticoagulant, heparin, which in 2004 was found able to inhibit invasion of SARS-CoV (CoV-1) and...

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Detalles Bibliográficos
Autores principales: Bertini, Sabrina, Alekseeva, Anna, Elli, Stefano, Pagani, Isabel, Zanzoni, Serena, Eisele, Giorgio, Krishnan, Ravi, Maag, Klaus P., Reiter, Christian, Lenhart, Dominik, Gruber, Rudolf, Yates, Edwin A, Vicenzi, Elisa, Naggi, Annamaria, Bisio, Antonella, Guerrini, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252607/
https://www.ncbi.nlm.nih.gov/pubmed/35322395
http://dx.doi.org/10.1055/a-1807-0168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252607/
https://www.ncbi.nlm.nih.gov/pubmed/35322395
http://dx.doi.org/10.1055/a-1807-0168

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