Cargando…

Application of CFD Numerical Simulation Image Imaging Technology in the Study of Droplet Microfluidic Multiphase Flow Characteristics

In order to study the problem that the flow in the internal channel of the microfluidic chip is different from that of the macroscopic system by the FD numerical simulation image imaging technology. Taking the liquid-liquid extraction of microfluidic chip as the research object, this paper analyzes...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Hao, Hu, Zihan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252693/
https://www.ncbi.nlm.nih.gov/pubmed/35833059
http://dx.doi.org/10.1155/2022/5851658
_version_ 1784740324392828928
author Li, Hao
Hu, Zihan
author_facet Li, Hao
Hu, Zihan
author_sort Li, Hao
collection PubMed
description In order to study the problem that the flow in the internal channel of the microfluidic chip is different from that of the macroscopic system by the FD numerical simulation image imaging technology. Taking the liquid-liquid extraction of microfluidic chip as the research object, this paper analyzes the theoretical basis, working principle, structural parameters, and the influence of working parameters on the fluid flow of liquid-liquid extraction. The results are as follows: when the inlet velocity of flowing liquid is 10(^(−5)) m/s, the diffusion efficiency can still be maintained at 95%; the double ψ-type aqueous phase showed laminar flow, the two-phase contact interface increased compared with the bottom flow rate, and the extraction efficiency increased to 98%; the extraction efficiency of double ψ type is higher than that of double Y-type: when the flow velocity ratio increases from v(aq) : v(oil)=1 : 2 to v(aq) : v(oil)=5 : 1, the extraction efficiency increases to 99.8%; the experimental extraction efficiency is compared with the diffusion efficiency simulated by simulation. The diffusion efficiency of the cross type is 1.05 times that of the extraction efficiency, and that of the cylindrical type is 1.04 times that of the extraction efficiency. In this study, CFD is used to simulate the characteristics of droplet microfluidic multiphase flow, which enriches the theoretical method and research experience of liquid-liquid laminar flow.
format Online
Article
Text
id pubmed-9252693
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-92526932022-07-12 Application of CFD Numerical Simulation Image Imaging Technology in the Study of Droplet Microfluidic Multiphase Flow Characteristics Li, Hao Hu, Zihan Contrast Media Mol Imaging Research Article In order to study the problem that the flow in the internal channel of the microfluidic chip is different from that of the macroscopic system by the FD numerical simulation image imaging technology. Taking the liquid-liquid extraction of microfluidic chip as the research object, this paper analyzes the theoretical basis, working principle, structural parameters, and the influence of working parameters on the fluid flow of liquid-liquid extraction. The results are as follows: when the inlet velocity of flowing liquid is 10(^(−5)) m/s, the diffusion efficiency can still be maintained at 95%; the double ψ-type aqueous phase showed laminar flow, the two-phase contact interface increased compared with the bottom flow rate, and the extraction efficiency increased to 98%; the extraction efficiency of double ψ type is higher than that of double Y-type: when the flow velocity ratio increases from v(aq) : v(oil)=1 : 2 to v(aq) : v(oil)=5 : 1, the extraction efficiency increases to 99.8%; the experimental extraction efficiency is compared with the diffusion efficiency simulated by simulation. The diffusion efficiency of the cross type is 1.05 times that of the extraction efficiency, and that of the cylindrical type is 1.04 times that of the extraction efficiency. In this study, CFD is used to simulate the characteristics of droplet microfluidic multiphase flow, which enriches the theoretical method and research experience of liquid-liquid laminar flow. Hindawi 2022-06-27 /pmc/articles/PMC9252693/ /pubmed/35833059 http://dx.doi.org/10.1155/2022/5851658 Text en Copyright © 2022 Hao Li and Zihan Hu. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Li, Hao
Hu, Zihan
Application of CFD Numerical Simulation Image Imaging Technology in the Study of Droplet Microfluidic Multiphase Flow Characteristics
title Application of CFD Numerical Simulation Image Imaging Technology in the Study of Droplet Microfluidic Multiphase Flow Characteristics
title_full Application of CFD Numerical Simulation Image Imaging Technology in the Study of Droplet Microfluidic Multiphase Flow Characteristics
title_fullStr Application of CFD Numerical Simulation Image Imaging Technology in the Study of Droplet Microfluidic Multiphase Flow Characteristics
title_full_unstemmed Application of CFD Numerical Simulation Image Imaging Technology in the Study of Droplet Microfluidic Multiphase Flow Characteristics
title_short Application of CFD Numerical Simulation Image Imaging Technology in the Study of Droplet Microfluidic Multiphase Flow Characteristics
title_sort application of cfd numerical simulation image imaging technology in the study of droplet microfluidic multiphase flow characteristics
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252693/
https://www.ncbi.nlm.nih.gov/pubmed/35833059
http://dx.doi.org/10.1155/2022/5851658
work_keys_str_mv AT lihao applicationofcfdnumericalsimulationimageimagingtechnologyinthestudyofdropletmicrofluidicmultiphaseflowcharacteristics
AT huzihan applicationofcfdnumericalsimulationimageimagingtechnologyinthestudyofdropletmicrofluidicmultiphaseflowcharacteristics