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DNAzymeBuilder, a web application for in situ generation of RNA/DNA-cleaving deoxyribozymes

Nucleic acid cleaving DNAzymes are versatile and robust catalysts that outcompete ribozymes and protein enzymes in terms of chemical stability, affordability and ease to synthesize. In spite of their attractiveness, the choice of which DNAzyme should be used to cleave a given substrate is far from o...

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Detalles Bibliográficos
Autores principales: Mohammadi-Arani, Razieh, Javadi-Zarnaghi, Fatemeh, Boccaletto, Pietro, Bujnicki, Janusz M, Ponce-Salvatierra, Almudena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252740/
https://www.ncbi.nlm.nih.gov/pubmed/35446426
http://dx.doi.org/10.1093/nar/gkac269