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DDGun: an untrained predictor of protein stability changes upon amino acid variants

Estimating the functional effect of single amino acid variants in proteins is fundamental for predicting the change in the thermodynamic stability, measured as the difference in the Gibbs free energy of unfolding, between the wild-type and the variant protein (ΔΔG). Here, we present the web-server o...

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Detalles Bibliográficos
Autores principales: Montanucci, Ludovica, Capriotti, Emidio, Birolo, Giovanni, Benevenuta, Silvia, Pancotti, Corrado, Lal, Dennis, Fariselli, Piero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252764/
https://www.ncbi.nlm.nih.gov/pubmed/35524565
http://dx.doi.org/10.1093/nar/gkac325

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