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CircadiOmics: circadian omic web portal

Circadian rhythms are a foundational aspect of biology. These rhythms are found at the molecular level in every cell of every living organism and they play a fundamental role in homeostasis and a variety of physiological processes. As a result, biomedical research of circadian rhythms continues to e...

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Autores principales: Samad, Muntaha, Agostinelli, Forest, Sato, Tomoki, Shimaji, Kohei, Baldi, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252794/
https://www.ncbi.nlm.nih.gov/pubmed/35657089
http://dx.doi.org/10.1093/nar/gkac419
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author Samad, Muntaha
Agostinelli, Forest
Sato, Tomoki
Shimaji, Kohei
Baldi, Pierre
author_facet Samad, Muntaha
Agostinelli, Forest
Sato, Tomoki
Shimaji, Kohei
Baldi, Pierre
author_sort Samad, Muntaha
collection PubMed
description Circadian rhythms are a foundational aspect of biology. These rhythms are found at the molecular level in every cell of every living organism and they play a fundamental role in homeostasis and a variety of physiological processes. As a result, biomedical research of circadian rhythms continues to expand at a rapid pace. To support this research, CircadiOmics (http://circadiomics.igb.uci.edu/) is the largest annotated repository and analytic web server for high-throughput omic (e.g. transcriptomic, metabolomic, proteomic) circadian time series experimental data. CircadiOmics contains over 290 experiments and over 100 million individual measurements, across >20 unique tissues/organs, and 11 different species. Users are able to visualize and mine these datasets by deriving and comparing periodicity statistics for oscillating molecular species including: period, amplitude, phase, P-value and q-value. These statistics are obtained from BIO_CYCLE and JTK_CYCLE and are intuitively aggregated and displayed for comparison. CircadiOmics is the most up-to-date and cutting-edge web portal for searching and analyzing circadian omic data and is used by researchers around the world.
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spelling pubmed-92527942022-07-05 CircadiOmics: circadian omic web portal Samad, Muntaha Agostinelli, Forest Sato, Tomoki Shimaji, Kohei Baldi, Pierre Nucleic Acids Res Web Server Issue Circadian rhythms are a foundational aspect of biology. These rhythms are found at the molecular level in every cell of every living organism and they play a fundamental role in homeostasis and a variety of physiological processes. As a result, biomedical research of circadian rhythms continues to expand at a rapid pace. To support this research, CircadiOmics (http://circadiomics.igb.uci.edu/) is the largest annotated repository and analytic web server for high-throughput omic (e.g. transcriptomic, metabolomic, proteomic) circadian time series experimental data. CircadiOmics contains over 290 experiments and over 100 million individual measurements, across >20 unique tissues/organs, and 11 different species. Users are able to visualize and mine these datasets by deriving and comparing periodicity statistics for oscillating molecular species including: period, amplitude, phase, P-value and q-value. These statistics are obtained from BIO_CYCLE and JTK_CYCLE and are intuitively aggregated and displayed for comparison. CircadiOmics is the most up-to-date and cutting-edge web portal for searching and analyzing circadian omic data and is used by researchers around the world. Oxford University Press 2022-06-03 /pmc/articles/PMC9252794/ /pubmed/35657089 http://dx.doi.org/10.1093/nar/gkac419 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of Nucleic Acids Research. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Web Server Issue
Samad, Muntaha
Agostinelli, Forest
Sato, Tomoki
Shimaji, Kohei
Baldi, Pierre
CircadiOmics: circadian omic web portal
title CircadiOmics: circadian omic web portal
title_full CircadiOmics: circadian omic web portal
title_fullStr CircadiOmics: circadian omic web portal
title_full_unstemmed CircadiOmics: circadian omic web portal
title_short CircadiOmics: circadian omic web portal
title_sort circadiomics: circadian omic web portal
topic Web Server Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252794/
https://www.ncbi.nlm.nih.gov/pubmed/35657089
http://dx.doi.org/10.1093/nar/gkac419
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