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Kinetochore Architecture Employs Diverse Linker Strategies Across Evolution

The assembly of a functional kinetochore on centromeric chromatin is necessary to connect chromosomes to the mitotic spindle, ensuring accurate chromosome segregation. This connecting function of the kinetochore presents multiple internal and external structural challenges. A microtubule interacting...

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Detalles Bibliográficos
Autores principales: Sridhar, Shreyas, Fukagawa, Tatsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252888/
https://www.ncbi.nlm.nih.gov/pubmed/35800888
http://dx.doi.org/10.3389/fcell.2022.862637