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Comprehensive multi-cohort transcriptional meta-analysis of muscle diseases identifies a signature of disease severity

Muscle diseases share common pathological features suggesting common underlying mechanisms. We hypothesized there is a common set of genes dysregulated across muscle diseases compared to healthy muscle and that these genes correlate with severity of muscle disease. We performed meta-analysis of tran...

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Detalles Bibliográficos
Autores principales: Walsh, C. J., Batt, J., Herridge, M. S., Mathur, S., Bader, G. D., Hu, P., Khatri, P., dos Santos, C. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253003/
https://www.ncbi.nlm.nih.gov/pubmed/35789175
http://dx.doi.org/10.1038/s41598-022-15003-1