Methyl probes in proteins for determining ligand binding mode in weak protein–ligand complexes

Structures of protein–ligand complexes provide critical information for drug design. Most protein–ligand complex structures are determined using X-ray crystallography, but where crystallography is not able to generate a structure for a complex, NMR is often the best alternative. However, the availab...

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Detalles Bibliográficos
Autores principales: Mohanty, Biswaranjan, Orts, Julien, Wang, Geqing, Nebl, Stefan, Alwan, Wesam S., Doak, Bradley C., Williams, Martin L., Heras, Begoña, Mobli, Mehdi, Scanlon, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253027/
https://www.ncbi.nlm.nih.gov/pubmed/35789157
http://dx.doi.org/10.1038/s41598-022-13561-y

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