Sex differences in heart mitochondria regulate diastolic dysfunction

Heart failure with preserved ejection fraction (HFpEF) exhibits a sex bias, being more common in women than men, and we hypothesize that mitochondrial sex differences might underlie this bias. As part of genetic studies of heart failure in mice, we observe that heart mitochondrial DNA levels and fun...

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Detalles Bibliográficos
Autores principales: Cao, Yang, Vergnes, Laurent, Wang, Yu-Chen, Pan, Calvin, Chella Krishnan, Karthickeyan, Moore, Timothy M., Rosa-Garrido, Manuel, Kimball, Todd H., Zhou, Zhiqiang, Charugundla, Sarada, Rau, Christoph D., Seldin, Marcus M., Wang, Jessica, Wang, Yibin, Vondriska, Thomas M., Reue, Karen, Lusis, Aldons J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253085/
https://www.ncbi.nlm.nih.gov/pubmed/35787630
http://dx.doi.org/10.1038/s41467-022-31544-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253085/
https://www.ncbi.nlm.nih.gov/pubmed/35787630
http://dx.doi.org/10.1038/s41467-022-31544-5

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