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Discriminating protein tags on a dsDNA construct using a Dual Nanopore Device

We report Brownian dynamics simulation results with the specific goal to identify key parameters controlling the experimentally measurable characteristics of protein tags on a dsDNA construct translocating through a double nanopore setup. First, we validate the simulation scheme in silico by reprodu...

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Detalles Bibliográficos
Autores principales: Seth, Swarnadeep, Rand, Arthur, Reisner, Walter, Dunbar, William B., Sladek, Robert, Bhattacharya, Aniket
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253098/
https://www.ncbi.nlm.nih.gov/pubmed/35787637
http://dx.doi.org/10.1038/s41598-022-14609-9

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