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Persistent red blood cells retain their ability to move in microcapillaries under high levels of oxidative stress

Oxidative stress is one of the key factors that leads to red blood cells (RBCs) aging, and impairs their biomechanics and oxygen delivery. It occurs during numerous pathological processes and causes anaemia, one of the most frequent side effects of cancer chemotherapy. Here, we used microfluidics to...

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Detalles Bibliográficos
Autores principales: Besedina, Nadezhda A., Skverchinskaya, Elisaveta A., Shmakov, Stanislav V., Ivanov, Alexander S., Mindukshev, Igor V., Bukatin, Anton S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253111/
https://www.ncbi.nlm.nih.gov/pubmed/35787676
http://dx.doi.org/10.1038/s42003-022-03620-5