Engineering probiotics to inhibit Clostridioides difficile infection by dynamic regulation of intestinal metabolism

Clostridioides difficile infection (CDI) results in significant morbidity and mortality in hospitalised patients. The pathogenesis of CDI is intrinsically related to the ability of C. difficile to shuffle between active vegetative cells and dormant endospores through the processes of germination and...

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Detalles Bibliográficos
Autores principales: Koh, Elvin, Hwang, In Young, Lee, Hui Ling, De Sotto, Ryan, Lee, Jonathan Wei Jie, Lee, Yung Seng, March, John C., Chang, Matthew Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253155/
https://www.ncbi.nlm.nih.gov/pubmed/35787625
http://dx.doi.org/10.1038/s41467-022-31334-z

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