Cargando…

The structure of erastin-bound xCT–4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis

Detalles Bibliográficos
Autores principales:	Yan, Renhong, Xie, Enjun, Li, Yaning, Li, Jin, Zhang, Yuanyuan, Chi, Ximin, Hu, Xueping, Xu, Lei, Hou, Tingjun, Stockwell, Brent R., Min, Junxia, Zhou, Qiang, Wang, Fudi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Nature Singapore 2022
Materias:	Letter to the Editor
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253326/ https://www.ncbi.nlm.nih.gov/pubmed/35352032 http://dx.doi.org/10.1038/s41422-022-00642-w

Ejemplares similares

Chemotherapeutic xCT inhibitors sorafenib and erastin unraveled with the synaptic optogenetic function analysis tool
por: Dahlmanns, Marc, et al.
Publicado: (2017)

How erastin assassinates cells by ferroptosis revealed
por: Gan, Boyi
Publicado: (2022)

Arginine Expedites Erastin-Induced Ferroptosis through Fumarate
por: Guo, Xinxin, et al.
Publicado: (2023)

The Role of Erastin in Ferroptosis and Its Prospects in Cancer Therapy
por: Zhao, Yuechen, et al.
Publicado: (2020)

Erastin/sorafenib induces cisplatin-resistant non-small cell lung cancer cell ferroptosis through inhibition of the Nrf2/xCT pathway
por: Li, Yu, et al.
Publicado: (2020)

The Protective Role of Mitochondrial Ferritin on Erastin-Induced Ferroptosis
por: Wang, Yue-Qi, et al.
Publicado: (2016)

Synergistic Effect of Erastin Combined with Nutlin-3 on Vestibular Schwannoma Cells as p53 Modulates Erastin-Induced Ferroptosis Response
por: He, Weiwei, et al.
Publicado: (2022)

Fascin enhances the vulnerability of breast cancer to erastin-induced ferroptosis
por: Chen, Cong, et al.
Publicado: (2022)

Neuroprotective effect of deferoxamine on erastin-induced ferroptosis in primary cortical neurons
por: Zhang, Yan, et al.
Publicado: (2020)

ATF3 promotes erastin-induced ferroptosis by suppressing system Xc(–)
por: Wang, Liyuan, et al.
Publicado: (2019)

Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC
por: Xue, Wei, et al.
Publicado: (2023)

Curcumin reverses erastin-induced chondrocyte ferroptosis by upregulating Nrf2
por: Zhou, Yizhao, et al.
Publicado: (2023)

Erastin-induced ferroptosis causes physiological and pathological changes in healthy tissues of mice
por: Zhao, Jing, et al.
Publicado: (2021)

Iron Administration Overcomes Resistance to Erastin-Mediated Ferroptosis in Ovarian Cancer Cells
por: Battaglia, Anna Martina, et al.
Publicado: (2022)

Erk1/2-Dependent HNSCC Cell Susceptibility to Erastin-Induced Ferroptosis
por: Savic, Dragana, et al.
Publicado: (2023)

Targeted exosome‐encapsulated erastin induced ferroptosis in triple negative breast cancer cells
por: Yu, Mengyu, et al.
Publicado: (2019)

Lipoxygenase‐mediated generation of lipid peroxides enhances ferroptosis induced by erastin and RSL3
por: Shintoku, Ryosuke, et al.
Publicado: (2017)

Cysteine Dioxygenase 1 Mediates Erastin-Induced Ferroptosis in Human Gastric Cancer Cells()
por: Hao, Shihui, et al.
Publicado: (2017)

Systematic identification of a nuclear receptor-enriched predictive signature for erastin-induced ferroptosis
por: Kwon, Ok-Seon, et al.
Publicado: (2020)

Nedd4 ubiquitylates VDAC2/3 to suppress erastin-induced ferroptosis in melanoma
por: Yang, Yongfei, et al.
Publicado: (2020)

Inhibition of autophagy rescues HT22 hippocampal neurons from erastin-induced ferroptosis
por: Hanke, Nora, et al.
Publicado: (2022)

Susceptibility to erastin‐induced ferroptosis decreases during maturation in a human oligodendrocyte cell line
por: Hoshino, Tomonori, et al.
Publicado: (2020)

Biochemical mechanism of erastin-induced ferroptotic cell death in neuronal cells: Role of PDI in ferroptosis
por: Hou, Ming-Jie, et al.
Publicado: (2023)

Erastin-induced ferroptosis is a regulator for the growth and function of human pancreatic islet-like cell clusters
por: Li, Xing Yu, et al.
Publicado: (2020)

Erastin induces ferroptosis in cervical cancer cells via Nrf2/HO-1 signaling pathway
por: Wei, Xiaoning, et al.
Publicado: (2023)

Blockade of GCH1/BH4 Axis Activates Ferritinophagy to Mitigate the Resistance of Colorectal Cancer to Erastin-Induced Ferroptosis
por: Hu, Qian, et al.
Publicado: (2022)

Activation of the reverse transsulfuration pathway through NRF2/CBS confers erastin-induced ferroptosis resistance
por: Liu, Nan, et al.
Publicado: (2019)

Upregulation of Nrf2 Signalling and the Inhibition of Erastin-Induced Ferroptosis by Ferulic Acid in MIN6 Cells
por: Kose, Tugba, et al.
Publicado: (2022)

miR-28-5p inhibits carcinogenesis in colon cancer cells and is necessary for erastin-induced ferroptosis
por: Hu, Jin-Cui, et al.
Publicado: (2020)

Ferroptosis inducer erastin sensitizes NSCLC cells to celastrol through activation of the ROS–mitochondrial fission–mitophagy axis
por: Liu, Ming, et al.
Publicado: (2021)

Erastin inhibits porcine epidemic diarrhea virus replication in Vero cells
por: Zhang, Hongliang, et al.
Publicado: (2023)

Transferrin-based radiolabeled probe predicts the sensitivity of human renal cancer cell lines to ferroptosis inducer erastin
por: Shibata, Yuki, et al.
Publicado: (2021)

Autophagy Regulates VDAC3 Ubiquitination by FBXW7 to Promote Erastin-Induced Ferroptosis in Acute Lymphoblastic Leukemia
por: Zhu, Ting, et al.
Publicado: (2021)

Overexpression of c‐Jun inhibits erastin‐induced ferroptosis in Schwann cells and promotes repair of facial nerve function
por: Gao, Dekun, et al.
Publicado: (2022)

Targeting histone deacetylase enhances the therapeutic effect of Erastin-induced ferroptosis in EGFR-activating mutant lung adenocarcinoma
por: Zhang, Tuo, et al.
Publicado: (2021)

Development of a primary microglia screening assay and its use to characterize inhibition of system x(c)(-) by erastin and its analogs
por: Figuera-Losada, Mariana, et al.
Publicado: (2017)

Monitoring and Regulating Intracellular GPX4 mRNA Using Gold Nanoflare Probes and Enhancing Erastin-Induced Ferroptosis
por: Liu, Xiaoyan, et al.
Publicado: (2022)

Erastin Reverses ABCB1-Mediated Docetaxel Resistance in Ovarian Cancer
por: Zhou, Hai-Hong, et al.
Publicado: (2019)

Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death
por: Kwon, Min-Young, et al.
Publicado: (2015)

The ferroptosis inducer erastin irreversibly inhibits system x(c)− and synergizes with cisplatin to increase cisplatin’s cytotoxicity in cancer cells
por: Sato, Mami, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_hgjmlhdks0sepiffe2t3rr8ote