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Sesamin protects against neurotoxicity via inhibition of microglial activation under high glucose circumstances through modulating p38 and JNK signaling pathways
Diabetes mellitus (DM), one of the principal causes of morbidity and mortality worldwide, is implicated in the progression of age-related neurodegenerative diseases (NDDs), in which microglial activation is a crucial mediator. Sesamin, a kind of phytochemical, shows inhibitory effects on microglial...
Autores principales: | Kongtawelert, Prachya, Kaewmool, Chayanut, Phitak, Thanyaluck, Phimphilai, Mattabhorn, Pothacharoen, Peraphan, Shwe, Thuzar Hla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253356/ https://www.ncbi.nlm.nih.gov/pubmed/35788665 http://dx.doi.org/10.1038/s41598-022-15411-3 |
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