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Behavioral- and blood-based biomarkers for Huntington's disease: Studies on the R6/1 mouse model with prospects for early diagnosis and monitoring of the disease

BACKGROUND: Huntington's disease (HD) is a genetic neurodegenerative disorder characterized by a triad of cognitive, psychiatric and motor symptoms. One of the main mechanisms of the disease, besides the aggregation of mutant proteins, is the chronic inflammation that occurs in patients long be...

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Detalles Bibliográficos
Autores principales:	Podlacha, Magdalena, Pierzynowska, Karolina, Gaffke, Lidia, Jerzemowska, Grażyna, Piotrowska, Ewa, Węgrzyn, Grzegorz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Full Length Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253406/ https://www.ncbi.nlm.nih.gov/pubmed/35799674 http://dx.doi.org/10.1016/j.bbih.2022.100482

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