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Mechanistic basis for Sgo1-mediated centromere localization and function of the CPC
Centromere association of the chromosomal passenger complex (CPC; Borealin-Survivin-INCENP-Aurora B) and Sgo1 is crucial for chromosome biorientation, a process essential for error-free chromosome segregation. Phosphorylated histone H3 Thr3 (H3T3ph; directly recognized by Survivin) and histone H2A T...
Autores principales: | Abad, Maria Alba, Gupta, Tanmay, Hadders, Michael A., Meppelink, Amanda, Wopken, J. Pepijn, Blackburn, Elizabeth, Zou, Juan, Gireesh, Anjitha, Buzuk, Lana, Kelly, David A., McHugh, Toni, Rappsilber, Juri, Lens, Susanne M.A., Jeyaprakash, A. Arockia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253516/ https://www.ncbi.nlm.nih.gov/pubmed/35776132 http://dx.doi.org/10.1083/jcb.202108156 |
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